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Biochemistry & Polymer Chemistry

Nucleotide

The monomer of nucleic acids, consisting of a nitrogenous base, a five-carbon sugar and a phosphate group.

Unit Dimensionless

In depth

Nucleotides link through phosphodiester bonds between the 3′ hydroxyl of one sugar and the 5′ phosphate of the next, giving the chain a direction. Beyond their role in nucleic acids, nucleotides serve as energy carriers and signalling molecules.

Examples in the real world

Adenosine triphosphate as the cell's energy currency; cyclic AMP as a second messenger.