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Organic Chemistry

Cannizzaro Reaction

The disproportionation of an aldehyde with no alpha hydrogen under concentrated alkali into an alcohol and a carboxylate.

Formula / equation 2RCHO + OH⁻ → RCH₂OH + RCOO⁻
Unit Dimensionless

In depth

With no alpha hydrogen available, the aldol pathway is blocked, so hydroxide adds to the carbonyl and the resulting alkoxide transfers a hydride to a second aldehyde molecule. One molecule is thereby oxidised and the other reduced.

Examples in the real world

Benzaldehyde with concentrated NaOH giving benzyl alcohol and sodium benzoate; methanal behaves the same way.