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Organic Chemistry

Stereoisomerism

Isomerism in which molecules have identical connectivity but differ in the spatial arrangement of their atoms.

Unit Dimensionless

In depth

Stereoisomers cannot be interconverted without breaking a bond or, for conformers, without rotation. They are divided into geometric isomers, arising from restricted rotation, and optical isomers, arising from chirality. Their separation often requires specialised chiral techniques.

Examples in the real world

Cis and trans but-2-ene; the two mirror-image forms of lactic acid.