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Acids, Bases & Salts

Henderson–Hasselbalch Equation

The equation giving the pH of a buffer from the pKa of its acid and the ratio of conjugate base to acid.

Formula / equation pH = pKa + log([A⁻]/[HA])
Unit Dimensionless

In depth

The equation shows that pH depends on the ratio of the two components rather than their absolute concentrations, which is why dilution barely changes a buffer's pH. It is derived from the Ka expression by taking logarithms and is accurate when both components are present in reasonable amounts.

Examples in the real world

A buffer with twice as much acetate as acetic acid has pH = 4.76 + log 2 = 5.06.