Column Chromatography
A preparative technique in which a mixture is separated by passing it down a vertical column packed with stationary phase.
Unit
g
In depth
Components elute at different times and are collected as separate fractions, allowing purified material to be recovered in gram quantities. Flash chromatography speeds the process by applying gas pressure, and it is the workhorse purification of every synthetic laboratory.
Examples in the real world
Purifying a synthetic product on a silica column eluted with a hexane–ethyl acetate mixture.