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Biophysics & Medical Physics

Cytoskeleton Mechanics

The study of the mechanical properties, viscoelasticity, and force generation of the intracellular filament network (actin, microtubules, intermediate filaments).

Governing formula Flexural Rigidity EI = E_young × I_area_moment
SI unit pN·μm² (Bending Stiffness)

In depth

Microtubules exhibit high flexural rigidity (stiff structural beams), while actin filaments form dynamic contractile networks governed by myosin motors, generating mechanical forces for cell division and motility.

Examples in the real world

Actin filament polymerization generating mechanical protrusive forces for cell migration.