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Biochemistry & Polymer Chemistry

Double Helix

The structure of DNA, in which two antiparallel polynucleotide strands wind around a common axis.

Formula / equation 10.5 base pairs per turn
Unit nm

In depth

The sugar–phosphate backbones lie on the outside and the hydrogen-bonded base pairs stack in the core, where base stacking contributes as much stability as the hydrogen bonds. The 2 nm-wide helix has major and minor grooves through which proteins read the sequence.

Examples in the real world

Watson and Crick's 1953 model, built on Franklin's X-ray diffraction photograph.