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Biophysics & Medical Physics

Brachytherapy

An internal radiation therapy technique where sealed radioactive sources are placed directly inside or adjacent to a tumor.

Governing formula Inverse Square Dose Falloff: D(r) ∝ 1 / r²
SI unit Gy/h (High or Low Dose Rate)

In depth

By placing radioisotope seeds (like I-125, Pd-103, or Ir-192) directly inside target tissue, inverse-square law dose falloff delivers maximum radiation to the tumor while minimizing dose to surrounding normal organs.

Examples in the real world

Permanent Iodine-125 seed implantation treating localized prostate cancer.