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Biophysics & Medical Physics

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Patch Clamp Technique Biophysics & Medical Physics pA (Picoamperes) & GΩ (Gigaohm Resistance) An electrophysiological laboratory technique used to record ion currents flowing through single individual ion channel proteins in cell membranes. I_single_channel ~ 1–10 pA (Gigaohm Seal Measurement) Poiseuille's Law of Blood Flow Biophysics & Medical Physics m³/s or L/min (Volumetric Flow Rate) A fluid dynamics equation governing laminar viscous fluid flow through a cylindrical vascular pipe. Q = (π r⁴ ΔP) / (8 η L) Positron Emission Tomography (PET Scan) Biophysics & Medical Physics MBq (Activity) & Standardized Uptake Value (SUV) A 3D nuclear medicine imaging technique detecting pairs of 511 keV gamma photons emitted during positron annihilation to map metabolic activity. Coincidence Detection of 180° Back-to-Back 511 keV Gamma Photons Protein Folding Biophysics & Medical Physics kJ/mol (Conformational Stability) The physical process by which a polypeptide chain folds spontaneously into a characteristic 3D functional native structure. Energy Funnel Concept: Minimizing Native State Free Energy G Proton Therapy Biophysics & Medical Physics MeV (Proton Beam Energy ~70–250 MeV) An advanced form of external beam radiation therapy utilizing accelerated proton beams to destroy cancerous tumors. Bragg Peak Energy Deposition Curve: (-dE/dx) ∝ 1 / v² Pulse Oximetry Biophysics & Medical Physics Percentage (% SpO₂) A non-invasive medical monitoring method measuring arterial blood oxygen saturation (SpO₂) using differential optical absorption of red and infrared light. Ratio R = (AC₆₆₀/DC₆₆₀) / (AC₉₄₀/DC₉₄₀) ⇒ % SpO₂